Drugs can Also be Used to Fight Diabetes
5th June, 2010 - Posted by admin - No Comments
According to national statistics of diabetes, 2011, by the National Clearinghouse on Diabetes (NDIC), provided about 10.9 million, or suffer 26.9% of Americans over 65 have diabetes. In addition, suffering 215, 000 or 0.26% of the respondents under 20 years of diabetes type 1 or type 2. Nearly 1.9 million people aged 20 or older were new with the disease diagnosed in 2010. Diabetes is a leading cause of kidney disease, amputations, blindness, diseases of the nervous system, hypertension, cardiovascular diseases and stroke. Avandamet and Janumet are two very effective anti-diabetic drugs in Canada that can help treat the disease.
Drugs in Canada: Avandamet and Janumet
Before buying this antidiabetics in Canada, it is important to know their customs, the mechanism and side effects:
Drugs in Canada: Mechanism Avandamet
One of the most popular drugs in Canada, Avandamet with proper diet and exercise to treat type 2 diabetes taken. It contains two oral antidiabetic medicine called metformin hydrochloride and rosiglitazone maleate. Avandamet works by improving insulin sensitivity and blood sugar control in diabetics.
In type 2 diabetes, the pancreas produces insulin, the body is not enough to regulate blood sugar levels. In addition, the body can not effectively use available insulin. The two active ingredients in Avandamet take different modes of action:
Rosiglitazone maleate: He is a member of the class of drugs called thiazolidinediones. It makes cells of the body (liver, fat and muscle mass) more sensitive to insulin. This helps the body make better use of available insulin.
Metformin hydrochloride: He is a member of the class of drugs called biguanides. It works by inhibiting the production of glucose and reduction of intestinal absorption of glucose.
Avandamet Side Effects
Some common side effects of Avandamet are:
Headache
Diarrhea
Nausea
Vomiting and stomach pain
Fatigue
Back and joint pain
Drugs in Canada: Mechanism Janumet
Janumet is a medicine for diabetes FDA-approved oral treatment for the treatment of type 2 diabetes. The drug is a combination of two drugs sitagliptin and metaformin, to reduce blood sugar in type 2 diabetics. Metaformin this Janumet works in the same way that it works in Avandamet.
However, sitagliptin has a different mode of action. It regulates the levels of insulin and lowers blood sugar levels in diabetics type 2. Incretin hormones, such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) released by the intestine after a meal. These hormones play an important role in increasing the production of insulin from the pancreas and reduces blood sugar levels. Sitagliptin inhibits the action of DPP-4 enzyme, the GIP and GLP-1 destroyed. These are the values of GIP and GLP-1 increases in the body resulting from the increased insulin production and less glucose in the blood.
Janumet Side Effects
Some common side effects of Janumet are:
Abdominal pain
Diarrhea
Nausea and vomiting
Hypoglycemia
Weakness
Stuffy or runny nose
Related posts:
No Comments
No Comments
Leave a reply